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A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
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[Deodorants and antiperspirants].

M-C Martini1

  • 1109, route de Limonest, 69380 Lissieu, France.

Annales De Dermatologie Et De Venereologie
|April 7, 2020
PubMed
Summary
This summary is machine-generated.

Deodorants and antiperspirants differ significantly in their active ingredients and mechanisms. Antiperspirants, containing aluminum compounds, can cause skin acidification, while deodorants may lead to bacterial resistance or allergic reactions from fragrances.

Keywords:
Aluminium chlorhydrateAluminium chlorohydrateAluminium-zirconium complexAntiperspirantAntisepticsAntiseptiquesAntitranspirantComplexe aluminium-zirconiumDeodorantDéodorantTriclosan

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Area of Science:

  • Cosmetic Science
  • Dermatology
  • Toxicology

Background:

  • Deodorants and antiperspirants are often confused, though they utilize distinct active ingredients and mechanisms.
  • Antiperspirants function as deodorants by preventing substrate decomposition but pose formulation challenges due to skin acidification from aluminum compounds.
  • Concerns exist regarding the potential genotoxicity and breast cancer link with systemic aluminum, though topical absorption is considered low.

Purpose of the Study:

  • To differentiate the mechanisms and potential risks associated with deodorants and antiperspirants.
  • To highlight the chemical properties and formulation considerations for antiperspirants.
  • To discuss the safety concerns and regulatory aspects of ingredients used in both product types.

Main Methods:

  • Comparative analysis of active ingredients and their modes of action.
  • Review of scientific literature on the toxicology and safety of aluminum, zirconium, antiseptics, and fragrances.
  • Examination of formulation challenges and solutions for antiperspirants.

Main Results:

  • Antiperspirants utilize aluminum chlorohydrate (ACH) or aluminum-zirconium complexes, causing skin acidification requiring emollients and pH regulators.
  • Deodorants may contain antiseptics like triclosan, potentially inducing bacterial resistance.
  • Axillary dermatitis is a risk with deodorants due to allergenic fragrances and essential oils.

Conclusions:

  • Antiperspirants and deodorants have different safety profiles and formulation requirements.
  • While topical aluminum absorption is low, concerns about systemic effects and zirconium toxicity persist.
  • Fragrance allergies are a significant issue in deodorant-associated dermatitis.