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Segmentation errors and motion artifacts in OCT-A associated with epiretinal membranes.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Idiopathic epiretinal membrane (ERM) is a common condition affecting vision.
  • Optical coherence tomography-angiography (OCT-A) is a key imaging modality for retinal evaluation.
  • Accurate segmentation is crucial for reliable OCT-A analysis.

Purpose of the Study:

  • To investigate segmentation errors, image quality, and motion artifacts in OCT-A of eyes with ERM.
  • To compare OCT-A findings in ERM patients with healthy controls.

Main Methods:

  • Prospective observational study including 39 eyes with ERM and 40 healthy eyes.
  • Automated segmentation performed using integrated software.
  • Evaluation of segmentation accuracy (deviation > 50 μm), motion artifacts, and image quality index.

Main Results:

  • Segmentation errors occurred in 64.1% of ERM patients, particularly at the inner plexiform layer and internal limiting membrane.
  • The retinal pigment epithelial layer showed high segmentation accuracy (96.7%).
  • Image quality index was 7.2 ± 0.9 in ERM patients, with no significant difference between phakic and pseudophakic eyes.

Conclusions:

  • OCT-A image quality is compromised in ERM patients due to motion artifacts and segmentation errors.
  • Inaccurate segmentation leads to erroneous en-face OCT-A images and unreliable quantification.
  • Careful review of OCT-A is necessary in ERM cases to mitigate diagnostic inaccuracies.