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Updated: Dec 24, 2025
Synthesizing Sodium Tungstate and Sodium Molybdate Microcapsules via Bacterial Mineral Excretion
Published on: January 30, 2018
Preparation and enzymatic application of flower-like hybrid microcapsules through a biomimetic mineralization
Jiafu Shi1, Shaohua Zhang, Xiaoli Wang
1Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China. zhyjiang@tju.edu.cn.
Abstract:
Fast and quantitative adsorption of molecules may confer hybrid microcapsules high performance in specific applications, such as biocatalysis, biosensing, drug delivery, and so on. Engineering the chemical/topological structures of the capsule wall renders great potential to achieve this goal. In the present study, flower-like microcapsules are prepared through a biomimetic mineralization approach. Briefly, protein-hybrid microflowers are firstly synthesized through enzyme-induced precipitation of Cu3(PO4)2, which are subsequently utilized as templates for alternative deposition of the protamine layer and the silica layer through biomimetic silicification assisted by layer-by-layer (LbL) assembly. After treatment with EDTA, the flower-like protamine/silica hybrid (FPSH) microcapsules are obtained. Additionally, the hybrid capsule wall also endows the FPSH microcapsules with desirable pH, temperature and storage stability. Hopefully, our approach may provide a promising alternative to increase the efficiency of catalysis, drug delivery, etc.
