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Published on: June 12, 2021
Internal polymer scaffolding in lipid-coated microbubbles for control of inertial cavitation in ultrasound
Shih-Tsung Kang1, Jian-Liang Lin, Chung-Hsin Wang
1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Taiwan. ckyeh@mx.nthu.edu.tw.
Abstract:
A lipid-polymer composite structure was developed for tuning of inertial cavitation activity of microbubbles under ultrasound exposure. The incorporation of a thin layer of polymer networks inside the lipid monolayer resulted in marked reduction in the inertial cavitation dose. This strategy has the potential to increase the safety of ultrasound theranostic applications assisted by microbubble cavitation.
