Modulating aggregation-induced emission via a non-conjugated linkage of fluorophores to tetraphenylethenes
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Updated: Dec 24, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Xie Han1, Bibo Zhang, Jianhua Chen
1Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China. yinj@mail.ccnu.edu.cn.
Abstract:
A fluorophore consisting of two fluorescent moieties could display unusual optical behaviors that are unattainable in a single-fluorophore compound. Herein we reported two "dual-fluorophore" dyes: DNS-linked tetraphenylethene demonstrates bright aggregation-induced emission, while NBD-linked tetraphenylethene exhibits aggregation-caused quenching. Our results have important implications for engineering emission behaviors of molecular aggregates for practical applications.
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