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Updated: Dec 24, 2025
Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling
Published on: June 9, 2023
[Submucosal laser ablation of internal hemorrhoids]
A Yu Titov1, I V Kostarev1, L A Blagodarny2
1A.N. Ryzhikh State Scientific Center of Coloproctology of the Ministry of Health of Russia, Moscow, Russia.
Objective:
To analyze efficacy and safety of submucosal laser ablation of internal hemorrhoids (SLT).
Material And Methods:
Systematic review included 10 articles published in electronic databases PubMed, Cochrane Library, Elibrary until January 2019. There were only full-text publications from prospective clinical trials devoted to submucosal laser ablation in the treatment of hemorrhoids. Isolated SLT was used in 4 trials, combination with other minimally invasive procedures was reported in 6 reports.
Results:
SLT was predominantly used in the treatment of hemorrhoids grade 2-3. Efficacy of procedure was 91.1-100% after 6 months and 87.5-100% after 12 months. Intra- and postoperative complications included intraoperative bleeding (8.4%), perianal and external piles edema (8.2%), postoperative bleeding (2.7%), urinary retention (1.2%), anal fistula (0.6%), perianal abscess (0.14%).
Conclusion:
Submucosal laser ablation is quite effective and safe option for treatment of hemorrhoids grade 2-3. However, further researches are required considering the absence of clear recommendations on laser beam parameters, indications for procedure and data on long-term outcomes.
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