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Updated: Dec 24, 2025

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
Published on: November 29, 2018
Cutting-Edge Evaluation of Male Infertility
Ujval Ishu Pathak1, Joseph Scott Gabrielsen2, Larry I Lipshultz1
1Scott Department of Urology, Baylor College of Medicine, 6624 Fannin Street, Suite 1700, Houston, TX 77030, USA.
Abstract:
A male factor is a contributor in 50% of cases of infertility. Although assisted reproductive techniques can often bypass the need to improve semen parameters, the evaluation of the infertile man remains critical. Current methods for evaluating the infertile man are discussed, beginning with the basic workup that all suspected infertile men should undergo, followed by subsequent evaluation steps. Although the fundamental components of the evaluation have remained consistent, several new tools are available to assist in identifying the underlying etiology. As our understanding of male fertility expands, the technologies available to diagnose and ultimately treat it continue to evolve.
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