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Personalized Medicine in Infertile Men
Nicolás Garrido1, Irene Hervás1
1Fundación Instituto Valenciano de Infertilidad (FIVI), Instituto Universitario IVI (IUIVI), Avda. Fernando Abril Martorell, nº106, Torre A, Planta 1(a), Valencia 46026, Spain.
The Urologic Clinics of North America
|April 11, 2020
Summary
New diagnostic methods using omics techniques can identify novel biomarkers for male infertility. These advancements promise noninvasive diagnosis and improved sperm selection for personalized medicine.
Area of Science:
- Reproductive biology and personalized medicine.
Background:
- Current male infertility diagnosis relies on spermiogram, which lacks comprehensive fertile potential assessment.
- There is a critical need for advanced diagnostic tools beyond traditional methods.
Purpose of the Study:
- To explore the potential of omics techniques in identifying new biomarkers for male infertility.
- To advance the diagnosis and treatment strategies for male reproductive health.
Main Methods:
- Application of omics technologies (genomics, metabolomics, etc.) to analyze male reproductive health data.
- Identification and validation of novel biomarkers from genetic and metabolic profiles.
Main Results:
- Omics approaches generate vast datasets revealing numerous potential infertility biomarkers.
- Identified biomarkers range from specific genes to metabolites.
Conclusions:
- Omics-derived biomarkers offer a promising avenue for noninvasive male infertility diagnosis.
- These biomarkers could significantly improve sperm selection techniques in assisted reproduction.
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