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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
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An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Updated: Dec 24, 2025

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
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Osteoporosis evaluation through full developed speckle imaging.

Marcello Magri Amaral1, Matheus Del-Valle2,3, Marcus Paulo Raele2

  • 1Instituto Cientifico e Tecnologico - Universidade Brazil, São Paulo, Brazil.

Journal of Biophotonics
|April 12, 2020
PubMed
Summary

Laser speckle imaging (LSI) can differentiate healthy and osteoporosis-affected jawbones. This safer, non-ionizing radiation technique shows promise for assessing alveolar bone lesions.

Keywords:
laser speckle imagemandiblemaxillaoptical diagnosisosteoporosis evaluation

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Area of Science:

  • Biomedical Engineering
  • Optical Imaging
  • Oral Biology

Background:

  • Osteoporosis reduces bone density, weakening bone structure.
  • Current diagnostic methods use ionizing radiation, posing health risks.
  • Optical techniques offer a safer alternative but are limited to bone tissue analysis.

Purpose of the Study:

  • To explore laser speckle imaging (LSI) for differentiating healthy and osteoporotic maxilla and mandible bones.
  • To assess the feasibility of using LSI in the oral cavity to overcome tissue limitations.
  • To investigate LSI's potential for diagnosing osteoporosis lesions in alveolar bone.

Main Methods:

  • Simulated osteoporosis lesions using acid attack on bone samples.
  • Evaluation using optical profilometry and laser speckle imaging (LSI).
  • Analysis of image parameters: speckle contrast ratio and patches ratio using custom software.

Main Results:

  • The speckle contrast ratio effectively differentiated sound from osteoporotic bone tissue.
  • A negative correlation was observed between the speckle patches ratio and roughness.
  • LSI demonstrated capability in assessing simulated osteoporosis lesions.

Conclusions:

  • Laser speckle imaging (LSI) is a promising non-ionizing radiation technique for osteoporosis assessment.
  • LSI can differentiate healthy and osteoporotic alveolar bone in an in vitro model.
  • This optical method offers a safer alternative for diagnosing bone density reduction in the oral cavity.