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Olfactory Dysfunction and Chronic Rhinosinusitis.

Omar G Ahmed1, Nicholas R Rowan1

  • 1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, 601 North Caroline Street, 6th floor, Suite 6164, Baltimore, MD 21287, USA.

Immunology and Allergy Clinics of North America
|April 13, 2020
PubMed
Summary
This summary is machine-generated.

Olfactory dysfunction (OD), a common symptom in chronic rhinosinusitis (CRS), significantly impacts quality of life. Treatments for CRS-related smell loss show variable effectiveness.

Keywords:
Chronic rhinosinusitisOlfactionOlfactory dysfunctionOlfactory loss

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Area of Science:

  • Otolaryngology
  • Rhinology
  • Neuroscience

Background:

  • Olfactory dysfunction (OD) is a primary symptom in chronic rhinosinusitis (CRS), affecting 60-80% of patients.
  • OD is more prevalent in CRS with nasal polyposis (CRSwNP) than without (CRSsNP).
  • Reduced smell significantly diminishes quality of life (QOL), impacting mood and food enjoyment.

Purpose of the Study:

  • To detail the prevalence and impact of olfactory dysfunction in chronic rhinosinusitis.
  • To explore the relationship between olfactory dysfunction and patient-reported outcomes.
  • To review the variable treatment responses for olfactory dysfunction in CRS.

Main Methods:

  • Utilized objective measures to assess the degree of olfactory dysfunction.
  • Employed subjective measures to evaluate the impact of olfactory dysfunction on patients.
  • Reviewed existing literature on medical and surgical treatment responses for OD in CRS.

Main Results:

  • Olfactory dysfunction is a cardinal symptom of CRS, with high prevalence (60-80%).
  • Patients with CRSwNP experience OD more frequently than those with CRSsNP.
  • Decreased olfactory function is linked to reduced QOL, depression, and diminished food enjoyment.

Conclusions:

  • Olfactory dysfunction is a significant and prevalent issue in chronic rhinosinusitis.
  • The impact of OD on patient quality of life is substantial.
  • Current medical and surgical treatments for OD in CRS demonstrate variable efficacy.