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Right Ventricular Failure and Congenital Heart Disease
Payton Kendsersky1, Cary Ward2
1Duke University Medical Center, Box 2819, Durham, NC 27710, USA.
Cardiology Clinics
|April 15, 2020
Summary
Improved survival in adults with congenital heart disease (CHD) highlights long-term complications, particularly right ventricle impact. Understanding these issues is crucial for managing morbidity and mortality in this growing patient population.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Adult Congenital Heart Disease
Background:
- Advances in prenatal detection, surgical techniques, and specialized care have increased survivorship for patients with congenital heart disease into adulthood.
- Long-term complications associated with congenital and repaired heart conditions are becoming increasingly evident in the adult population.
- Heart failure in adult congenital heart disease (ACHD) patients carries a significant mortality rate of approximately 4%.
Purpose of the Study:
- To elucidate the long-term complications in adult patients with congenital heart disease.
- To focus on the impact of congenital malformations, palliations, and residual defects on right ventricle physiology.
- To discuss the influence of these factors on morbidity and mortality in specific ACHD conditions.
Main Methods:
- Review and discussion of existing literature and clinical data regarding adult congenital heart disease.
- Focus on specific congenital heart conditions: atrial septal defects, Ebstein anomaly, Tetralogy of Fallot, transposition of the great vessels, and single right ventricle physiology.
- Analysis of the relationship between congenital heart defects, surgical repair, and resultant right ventricular impact.
Main Results:
- Increased survivorship into adulthood for patients with congenital heart disease.
- Clearer understanding of long-term complications affecting adult congenital heart disease patients.
- Right ventricle physiology is significantly impacted by various congenital malformations and repairs, influencing patient outcomes.
Conclusions:
- Long-term management of adult congenital heart disease requires a comprehensive understanding of the impact on right ventricle function.
- Specific conditions like atrial septal defects, Ebstein anomaly, Tetralogy of Fallot, transposition of the great vessels, and single right ventricle physiology present unique challenges.
- Addressing these complexities is vital for improving morbidity and mortality rates in the growing adult congenital heart disease population.
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