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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
[Community-acquired pneumonia]
1Medizinische Klinik III, Universitätsklinikum Schleswig-Holstein, Campus Lübeck.
Abstract:
Diagnostic tools are essential for the physician to reach a correct diagnosis of community-acquired pneumonia, to determine the pathogen, and to estimate the prognosis of individual patients. X-ray of the chest remains the "gold standard" for identification of pneumonia. Modern inflammatory markers such as C-reactive protein and in the future procalcitonin are essential for the differential diagnosis and follow-up. The microbiology tests include, besides classic bacterial cultures, urinary antigen tests for Streptococcus pneumoniae and Legionella pneumophila. A simple prognostic score has been developed to help the physician to decide if the patient needs hospitalization.
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