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Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

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Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
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Updated: Dec 24, 2025

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

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[Infectious diseases in immunocompromised patients].

H Guberina1, M Sava1, O Witzke1,2

  • 1Klinik für Infektiologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstraße 55, 45147 Essen, Deutschland.

Der Nephrologe
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

Patients with weakened immune systems face higher risks from infections, especially after organ transplants. Early detection and proactive management are crucial for preventing severe complications and improving outcomes in immunocompromised individuals.

Keywords:
Immunocompromised hostInfectious complicationsOrgan transplantationProphylaxisVaccination

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Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
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Related Experiment Videos

Last Updated: Dec 24, 2025

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Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
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Area of Science:

  • Immunology
  • Infectious Diseases
  • Transplantation Medicine

Context:

  • Immunocompromised patients, including those with primary immunodeficiency or on immunosuppressive therapy, are at elevated risk for infectious disease complications.
  • Infections represent the second leading cause of mortality following solid organ transplantation.
  • The clinical presentation of infections in immunosuppressed individuals can be atypical, complicating diagnosis and treatment.

Purpose:

  • To highlight the significant risks of infectious diseases in immunosuppressed patients.
  • To emphasize the challenges in diagnosing and treating infections in this vulnerable population.
  • To underscore the importance of routine prophylactic measures and vigilant patient surveillance.

Summary:

  • Patients with immunodeficiency or undergoing immunosuppressive treatment require careful monitoring for infections.
  • Atypical symptoms in these patients pose diagnostic and therapeutic challenges, particularly with viral and opportunistic pathogens.
  • Early diagnosis through diligent surveillance is essential for timely intervention and management of infectious diseases.

Impact:

  • Implementing routine prophylactic strategies and enhanced patient surveillance can mitigate infectious disease risks.
  • Improved diagnostic approaches and timely treatment initiation are critical for reducing morbidity and mortality in immunosuppressed patients.
  • This understanding is vital for optimizing patient care and outcomes in transplantation and other immunocompromising conditions.