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Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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Cutaneous interaction with visible light: What do we know?

Leah Cohen1, Merrick A Brodsky2, Raheel Zubair3

  • 1Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Journal of the American Academy of Dermatology
|April 15, 2020
PubMed
Summary

Visible light, once considered inert, can cause skin issues like redness and pigment changes. This review examines its role in dermatologic diseases, including hyperpigmentation disorders like melasma.

Keywords:
antioxidantsblue lightiron oxidemelasmapigmentationpostinflammatory hyperpigmentationreactive oxygen speciessunscreenultraviolet lightvisible light

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Area of Science:

  • Dermatology
  • Photobiology

Background:

  • Visible light is used therapeutically in dermatology.
  • It was previously thought to be inert compared to UV and IR radiation.
  • Recent studies show visible light can cause erythema and pigmentary changes.

Purpose of the Study:

  • To provide an evidence-based review of visible light's effects on the skin.
  • To focus on its role in dermatologic diseases, particularly hyperpigmentation.

Main Methods:

  • Literature review of existing studies on visible light and skin.
  • Analysis of evidence regarding cutaneous effects.

Main Results:

  • Visible light can induce erythema in lighter skin tones.
  • It can cause pigmentary alterations in darker skin types.
  • Concerns about potential cutaneous damage are growing.

Conclusions:

  • Visible light has previously unrecognized cutaneous effects.
  • It plays a role in dermatologic conditions like melasma and postinflammatory hyperpigmentation.
  • Further research is needed to understand and manage these effects.