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Supramolecular Hyaluronic Assembly with Aggregation-Induced Emission Mediated in Two Stages for Targeting Cell
Yang Yang1, Ya-Jun Jin1, Xin Jia1
1School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, P. R. China.
ACS Medicinal Chemistry Letters
|April 16, 2020
Abstract:
Supramolecular aggregation-induced emission (AIE) has become a research hotspot in cell imaging. Herein, supramolecular assembly with AIE effect was constructed in two stages, where adamantane modified tetraphenylethene self-assembly emitted weak fluorescence, and then after adding β-cyclodextrin modified hyaluronic acid, the formed nanoparticles enhanced AIE fluorescence for targeted cancer cell imaging.

