Related Experiment Video
Updated: Dec 23, 2025

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
Published on: July 20, 2022
Current status of pediatric mechanical circulatory support
Zachary A Spigel1, Junsang Cho2, Iki Adachi1
1Division of Congenital Heart Surgery, Michael E. DeBakey Department of Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Insights
Pediatric ventricular assist device (VAD) support has advanced significantly, but challenges remain. Future improvements in VAD therapy are crucial for better outcomes in children with heart conditions.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Mechanical Circulatory Support
Background:
- Pediatric mechanical circulatory support, particularly ventricular assist devices (VADs), has evolved rapidly.
- Continuous-flow VADs are now a standard option for children, mirroring adult applications.
- Despite advancements, pediatric VAD support requires further improvements beyond survival rates.
Purpose of the Study:
- To review the current state of pediatric VAD support.
- To identify existing challenges in pediatric VAD therapy.
- To highlight key areas for future clinical focus and improvement.
Main Methods:
- Review of current literature and clinical practices in pediatric VAD support.
- Analysis of recent findings and outcomes in pediatric VAD implantation.
- Identification of trends and challenges in the field.
Main Results:
- The number of pediatric VAD implants, especially continuous-flow VADs, is increasing.
- The HeartWare HVAD is widely used, but home discharge rates for pediatric patients are lower than in adults.
- Outcomes for children with complex congenital heart defects and single ventricle physiology remain suboptimal.
Conclusions:
- Pediatric VAD support is maturing, with ongoing advancements.
- Further research and clinical focus are needed to optimize VAD therapy for children.
- The potential for VADs as permanent therapy in pediatric patients is increasing.
Purpose Of Review:
The field of pediatric mechanical circulatory support has experienced exponential evolution in recent decades. With favorable complication profiles, implantable continuous-flow ventricular assist devices (VADs) have become a standard option in children, as has been seen in the adult counterpart. Nevertheless, there still exists room for further advances, not just for survival, but throughout the whole trajectory of treatment courses. With reviewing the current state of pediatric VAD support, including existing challenges, we aim to highlight the targets clinicians should focus on for further improvement of pediatric VAD support.
Recent Findings:
The field of pediatric VAD has been steadily growing, as evidenced by an increasing number of total VAD implants, particularly with continuous-flow VAD. Currently, HeartWare HVAD (Medtronic Inc., Mounds View, MN) is the most widely used continuous-flow VAD in children with excellent performance. However, only half of the children with HVAD are discharged home, which is drastically different from adult patients, suggesting that the pediatric field is still in the process of maturation. Additionally, outcomes of VAD support for complex congenital heart defect, particularly single ventricle physiology, remain suboptimal, despite an increasing number of such patients.
Summary:
With the ongoing advancement, the field of pediatric VAD support is undergoing a rapid maturation process. This will eventually lead to further paradigm changes, including the use of VAD as permanent therapy.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy V: Interprofessional Care
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Mechanical Ventilation I: Indication and Settings
Cardiomyopathy II: Dilated Cardiomyopathy

