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Neutrophilic Urticarial Dermatosis Without Underlying Systemic Disease
Ryan Gillihan1,2, Navid Farahbakhsh1,2, Kiran Motaparthi1,2
1Drs. Gillihan and Motaparthi are with the Department of Dermatology at the University of Florida in Gainesville, Florida.
The Journal of Clinical and Aesthetic Dermatology
|April 21, 2020
Summary
Neutrophilic urticarial dermatosis (NUD) is a rare skin condition. This case study shows NUD can occur without other health issues and effectively treated with low-dose dapsone.
Area of Science:
- Dermatology
- Immunology
Background:
- Neutrophilic urticarial dermatosis (NUD) is a rare inflammatory skin condition.
- NUD is poorly understood and often associated with systemic or autoinflammatory disorders.
Observation:
- This report details a case of NUD presenting without any underlying systemic conditions.
- The patient exhibited classic symptoms of NUD.
Findings:
- The patient's NUD demonstrated a significant and positive response to treatment with low-dose dapsone.
- This suggests dapsone may be an effective therapeutic option for NUD.
Implications:
- NUD can manifest independently of systemic diseases.
- Low-dose dapsone offers a potential treatment strategy for NUD, even in cases without associated systemic findings.
- Further research into NUD pathogenesis and treatment is warranted.
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