Haemoglobin H disease and cardiac surgery

Area of Science:

• Hematology
• Cardiovascular Surgery
• Anesthesiology

Background:

• Hemoglobin H disease is a significant alpha-thalassemia trait.
• Patients with hemoglobin H disease may require surgical intervention, including cardiac procedures.

Observation:

• Two cases of patients with hemoglobin H disease undergoing open-heart surgery were managed.
• Specific anesthetic challenges associated with hemoglobin H disease were observed.

Findings:

• The anesthetic management strategies for these complex cases are presented.
• Key problems related to anesthesia in the context of hemoglobin H disease were identified and discussed.

Implications:

• This case series provides insights into the perioperative care of patients with hemoglobin H disease.
• Understanding these anesthetic challenges can improve patient outcomes in similar surgical scenarios.