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Current Validated Medical Treatments: Pharmacologic Interventions.

Carol A Bauer1

  • 1Department of Otolaryngology Head and Neck Surgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.

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|April 27, 2020
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Summary
This summary is machine-generated.

Currently, no universally effective tinnitus medications exist. Research focuses on drugs to eliminate tinnitus perception or manage its associated quality-of-life impacts.

Keywords:
AnxietyClinical trialsDepressionNeurotransmittersPharmacologyPsychoacousticTinnitus

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Area of Science:

  • Otolaryngology
  • Pharmacology
  • Neurology

Background:

  • Tinnitus, the perception of sound without external source, significantly impacts quality of life.
  • Existing treatments for tinnitus are limited, with no universally curative medications available.
  • Pharmacologic strategies are broadly categorized into those targeting tinnitus perception and those managing associated comorbidities.

Purpose of the Study:

  • To review pharmacologic interventions for tinnitus.
  • To differentiate between treatments aiming to eliminate tinnitus perception and those managing its impact on quality of life.

Main Methods:

  • Literature review of pharmacologic interventions for tinnitus.
  • Categorization of drug therapies based on their therapeutic targets.

Main Results:

  • No current drug universally eliminates tinnitus.
  • Investigated drugs aim to either suppress tinnitus perception or alleviate associated symptoms like anxiety and depression.
  • Management of comorbidities is a key strategy to mitigate tinnitus' negative effects.

Conclusions:

  • Pharmacologic treatment of tinnitus remains challenging.
  • Future research may focus on novel drug targets for tinnitus suppression or improved management of its debilitating effects.