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Updated: Mar 21, 2026

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
Published on: August 24, 2017
Neuroscience of Tinnitus
1Department of Diagnostic Radiology, Southern Illinois University School of Medicine, Memorial Medical Center, 701 North 1st Street, Springfield, IL 62794-9662, USA.
Abstract:
Tinnitus is a consequence of changes in auditory and nonauditory neural networks following damage to the cochlea. Homeostatic compensatory mechanisms occur after hearing loss and these mechanisms alter the balance of excitatory and inhibitory neurotransmitters. In many individuals with hearing loss, chronic tinnitus and related phenomena emerge. Some people with tinnitus are disturbed by this subjective sensation. When auditory network dysfunction is coupled with limbic-gating dysfunction, an otherwise meaningless auditory percept such as tinnitus may acquire negative emotional features. The development of effective treatment options is enhanced by the understanding of the neural networks underpinning tinnitus.
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