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Vaccinations and Biologics.

Betty Hsiao1, Aisha Khan2, Insoo Kang1

  • 1Section of Rheumatology, Yale University School of Medicine, 300 Cedar Street, TAC Bldg, RM #525 PO Box 208031, New Haven, CT 06520-8031, USA; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

Infectious Disease Clinics of North America
|April 27, 2020
PubMed
Summary
This summary is machine-generated.

Biologics are crucial for autoimmune diseases but increase infection risk. Patients on biologics require careful vaccination management to prevent infections and optimize treatment benefits.

Keywords:
Autoimmune diseasesBiologicsImmunosuppressedInfectionsRheumatic diseasesVaccinationsVaccines

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Area of Science:

  • Immunology
  • Pharmacology
  • Infectious Diseases

Background:

  • Biologics have transformed autoimmune disease treatment.
  • Biologics can impair immune responses, raising infection risks.
  • Vaccinations can mitigate infection risks in immunocompromised patients.

Purpose of the Study:

  • To review recent literature and guidelines on vaccinations for patients receiving biologics.
  • To highlight the importance of vaccination status in biologic therapy.

Main Methods:

  • Literature review of recent articles and guidelines.
  • Synthesis of information regarding vaccination recommendations for patients on biologics.

Main Results:

  • Biologic therapies necessitate a thorough review of patient vaccination history.
  • Annual updates to vaccination status are recommended.
  • Vaccinations can prevent or reduce the severity of infections in patients on biologics.

Conclusions:

  • Vaccination is a critical component of managing patients on biologic therapies.
  • Proactive vaccination strategies are essential for maximizing benefits and minimizing adverse effects of biologics.