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Updated: Aug 11, 2026

Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
[Lymphoreticular cells in the human endometrial stroma]
F Buchholz1, H P Horny, J Dietl
1Frauenklinik der Universität Kiel.
Abstract:
The endometrium of 12 patients with a normal spontaneous uterine cycle was examined immunohistochemically with the indirect PAP-method using various monoclonal antibodies. Lymphoreticular cells, which are responsible for non-specific defense mechanisms and for the cell-mediated immune reactions were identified. In all phases of the normal cycle, high numbers of cells belonging to the mononuclear phagocyte system (MPS) and T-lymphocytes were detected in the endometrial stroma. The overwhelming majority of T-lymphocytes were found to be of the suppressor/cytotoxic cell type, while helper/inducer cells were seen only in comparably low numbers. B-lymphocytes were virtually absent from the endometrial stroma.
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