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[SARS-CoV-2 infection and solid organ transplantation]
Dela Golshayan1, John-David Aubert1,2, Roger Hullin3
1Centre de transplantation d'organes, Département de médecine et de chirurgie, CHUV et Université de Lausanne, 1011 Lausanne.
Revue Medicale Suisse
|April 30, 2020
Summary
Solid organ transplant recipients face risks from SARS-CoV-2 (COVID-19). This review covers COVID-19 incidence, clinical course, and management strategies for these vulnerable patients.
Area of Science:
- Medicine
- Immunology
- Infectious Diseases
Background:
- Solid organ transplantation is a vital treatment for end-stage organ disease.
- The COVID-19 pandemic presents unique challenges for transplant recipients and programs.
- Limited guidance exists for managing transplant patients during pandemics.
Purpose of the Study:
- To review the incidence and clinical outcomes of SARS-CoV-2 infection in solid organ transplant recipients.
- To discuss therapeutic strategies for COVID-19 in this population.
- To provide recommendations for managing transplant programs during healthcare resource scarcity.
Main Methods:
- Literature review of current knowledge on SARS-CoV-2 in solid organ transplant recipients.
- Analysis of incidence, clinical course, and treatment options.
- Synthesis of recommendations for transplant programs.
Main Results:
- Solid organ transplant recipients are a vulnerable group for SARS-CoV-2 infection.
- Specific challenges include treatment options and immunosuppression adjustments.
- The review consolidates existing data and expert opinions.
Conclusions:
- Effective management of COVID-19 in transplant recipients requires tailored strategies.
- Adaptable recommendations are crucial for maintaining transplant services during pandemics.
- Further research is needed to optimize care for this high-risk population.
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