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Group contributions to hydrophobicity and elution behaviour of pyridine derivatives in reversed-phase
F Gago1, J Alvarez-Builla, J Elguero
1Department of Pharmacology, University of Alcalá de Henares, Madrid, Spain.
Journal of Chromatography
|September 30, 1988
Abstract:
The mean hydrophobic contributions, pi*m, of substituents in a sample of 34 monosubstituted pyridines has been determined by using reversed-phase high-performance liquid chromatography. The values are compared with those obtained for benzene.