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Updated: Dec 22, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Targeting the Water Network in Cyclin G-Associated Kinase (GAK) with 4-Anilino-quin(az)oline Inhibitors

Christopher R M Asquith1,2, Graham J Tizzard3, James M Bennett4

  • 1Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Chemmedchem
|May 3, 2020
PubMed

Keywords:
WaterMapanilinoquinazolinesanilinoquinolinescyclin G-associated kinase (GAK)water networks

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