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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Severe acute respiratory illness surveillance for coronavirus disease 2019, India, 2020
Nivedita Gupta1, Ira Praharaj1, Tarun Bhatnagar2
1Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Insights
Sentinel surveillance of severe acute respiratory illness (SARI) patients in India detected 1.8% COVID-19 positivity. This data aids in targeting containment efforts and optimizing resource allocation for pandemic mitigation.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Sentinel surveillance of severe acute respiratory illness (SARI) patients is crucial for tracking coronavirus disease 2019 (COVID-19) transmission.
- SARI surveillance was implemented early in India's COVID-19 outbreak to monitor disease spread.
Purpose of the Study:
- To determine the positivity rate of COVID-19 among SARI patients in India.
- To characterize the demographic and epidemiological features of COVID-19 cases identified through SARI surveillance.
Main Methods:
- Real-time reverse transcription-polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 (E and RdRp genes) was performed on SARI patients.
- Data were collected from 41 sentinel sites across India starting February 15, 2020, and analyzed from the Virus Research and Diagnostic Laboratory Network.
Main Results:
- Out of 5,911 SARI patients tested, 104 (1.8%) were positive for COVID-19.
- COVID-19 cases were identified in 52 districts across 20 States/Union Territories.
- Positivity was higher in males and individuals over 50 years old; 39.2% of cases had no known contact or travel history.
Conclusions:
- Districts reporting COVID-19 cases among SARI patients require targeted containment strategies.
- Enhanced sentinel surveillance for COVID-19 in SARI patients is an effective approach for resource-efficient containment and mitigation.
Background & Objectives:
Sentinel surveillance among severe acute respiratory illness (SARI) patients can help identify the spread and extent of transmission of coronavirus disease 2019 (COVID-19). SARI surveillance was initiated in the early phase of the COVID-19 outbreak in India. We describe here the positivity for COVID-19 among SARI patients and their characteristics.
Methods:
SARI patients admitted at 41 sentinel sites from February 15, 2020 onwards were tested for COVID-19 by real-time reverse transcription-polymerase chain reaction, targeting E and RdRp genes of SARS-CoV-2. Data were extracted from Virus Research and Diagnostic Laboratory Network for analysis.
Results:
A total of 104 (1.8%) of the 5,911 SARI patients tested were positive for COVID-19. These cases were reported from 52 districts in 20 States/Union Territories. The COVID-19 positivity was higher among males and patients aged above 50 years. In all, 40 (39.2%) COVID-19 cases did not report any history of contact with a known case or international travel.
Interpretation & Conclusions:
COVID-19 containment activities need to be targeted in districts reporting COVID-19 cases among SARI patients. Intensifying sentinel surveillance for COVID-19 among SARI patients may be an efficient tool to effectively use resources towards containment and mitigation efforts.
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