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Related Experiment Video

Updated: Dec 22, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Modern Stents: Where Are We Going?

Ofer Kobo¹, Majdi Saada¹, Simcha R Meisel^1,2

¹Department of Cardiology, Hillel Yaffe Medical Center, Hadera, Israel.

Rambam Maimonides Medical Journal

|May 7, 2020

Summary

Newer drug-eluting stents (DES) significantly reduce restenosis and thrombosis after coronary angioplasty. These advanced DES are now the standard of care, offering excellent long-term results for patients.

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Last Updated: Dec 22, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

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Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention

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Published on: September 18, 2015

Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Biomedical Engineering

Background:

Coronary artery stenting is a primary treatment for coronary angioplasty.
Significant advancements in stent design and medical therapies have occurred.
Early drug-eluting stents (DES) improved outcomes but had limitations.

Purpose of the Study:

To review major advancements in coronary artery stenting technology.
To evaluate the safety and effectiveness of newer-generation DES.
To compare newer DES with early-generation DES and bioresorbable scaffolds.

Main Methods:

Review of technological developments in coronary stents.
Analysis of clinical data on newer-generation drug-eluting stents (DES).
Comparison of outcomes between different stent generations and bioresorbable scaffolds.

Main Results:

Newer-generation DES demonstrate negligible restenosis rates and low stent thrombosis risk.
Improved DES designs (thinner struts, novel polymers, new agents) enhance safety.
Bioresorbable vascular scaffolds have not shown further clinical benefits and exhibit increased thrombosis.

Conclusions:

Newer-generation DES, both durable and biodegradable polymer, are the standard of care.
These stents offer excellent long-term results across all patient and lesion subsets.
Continued innovation in DES technology improves patient outcomes in coronary angioplasty.