Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genome-Wide Identification, Expression and Tissue-Specific Epigenetic Modification Analysis of the <i>Su(var)3-9 SET</i> Gene Family in Soybean.

Biology·2026
Same author

The lactate-GPR81-AMIGO2 axis promotes pancreatic ductal adenocarcinoma progression and predicts poor prognosis.

Cellular signalling·2026
Same author

Clinical and MRI features for differentiating reactive lymphoid hyperplasia from hepatocellular carcinoma in non-cirrhotic chronic HBV patients.

European journal of radiology·2026
Same author

Periodontitis and systemic diseases: insights into the correlation, mechanisms, and clinical implications.

Frontiers in immunology·2026
Same author

A Single-Cell Atlas of Pan-Cancer Liver Metastasis Reveals Dynamic Cellular Programs Driving Metastatic Progression and Immune Modulation.

Research (Washington, D.C.)·2026
Same author

Quality and reliability of ground-glass nodule-related short Chinese videos on TikTok and Bilibili: a cross-sectional content analysis.

Journal of thoracic disease·2026

Related Experiment Video

Updated: Dec 22, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
07:41

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

9.4K

Construction of an integrated human osteosarcoma database, HOsDb, based on literature mining, microarray analysis,

Yifu Sun1, Lishan Wang2, Changkuan Li1

  • 1Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, 130033, P.R. China.

BMC Cancer
|May 8, 2020
PubMed
Summary

Osteosarcoma (OS) is a common bone cancer in adolescents. The HOsDb database integrates OS-related genes, transcription factors, SNPs, and miRNAs to advance understanding of this disease.

Keywords:
HOsDbOsteosarcomawww.hosdatabase.com

More Related Videos

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
04:25

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

11.0K
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.5K

Related Experiment Videos

Last Updated: Dec 22, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
07:41

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

9.4K
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
04:25

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

11.0K
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.5K

Area of Science:

  • Oncology
  • Genetics
  • Bioinformatics

Background:

  • Osteosarcoma (OS) is the most common primary bone cancer, particularly affecting adolescents.
  • Existing data on OS is fragmented, hindering comprehensive research and understanding.

Purpose of the Study:

  • To construct a publicly available, integrated database of human Osteosarcoma (OS) called HOsDb.
  • To consolidate diverse OS-related molecular information for researchers.

Main Methods:

  • Collected data from microarray analysis, existing databases, and PubMed literature searches.
  • Extracted information on OS-related genes, transcription factors (TFs), single nucleotide polymorphisms (SNPs), methylation sites, and microRNAs (miRNAs).

Main Results:

  • Identified 7191 OS tumor-related genes, 763 metastasis-related genes, and 1589 drug-related genes.
  • Cataloged extensive gene-TF and gene-miRNA interactions, alongside numerous SNPs, OS-related miRNAs, and genes with copy number variations or methylation sites.
  • Integrated all data into the HOsDb, accessible at www.hosdatabase.com.

Conclusions:

  • HOsDb serves as a comprehensive, accessible resource for OS research.
  • The database is expected to significantly enhance current knowledge and facilitate future studies on Osteosarcoma.