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Lemon seed allergy: a case presentation.

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  • 11Department of Adult Allergy, Guy's and St Thomas' NHS Foundation Trust, London, SE1 9RT UK.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
|May 8, 2020
PubMed
Summary
This summary is machine-generated.

A rare IgE-mediated hypersensitivity to lemon seed was identified in a patient experiencing recurrent anaphylaxis. This study reveals cross-reactivity between citrus seeds from related species, highlighting a potential cause for unexplained allergic reactions.

Keywords:
AdultAnaphylaxisCase reportCitrusFood hypersensitivityHybridisationImmunoglobulin ESeedTree Nut

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Area of Science:

  • Immunology
  • Allergology
  • Food Science

Background:

  • Investigating rare causes of hypersensitivity reactions.
  • Understanding IgE-mediated allergies to specific food components.
  • Exploring cross-reactivity patterns in food allergies.

Observation:

  • A 26-year-old female presented with recurrent anaphylaxis upon exposure to lemon seed.
  • Skin prick testing confirmed sensitization to lemon seed.
  • Cross-reactivity testing included various citrus seeds and foods from the Sapindale order.

Findings:

  • Demonstrated IgE-mediated hypersensitivity to lemon seed.
  • Identified a novel cross-sensitization pattern among citrus hybrid seeds with similar ancestral origins.
  • Established a link between lemon seed exposure and anaphylaxis.

Implications:

  • Suggests citrus seed allergy should be considered in adult patients with unexplained or recurrent anaphylaxis.
  • Highlights the importance of detailed allergen testing in complex allergy cases.
  • Provides new insights into cross-reactivity within the Sapindale order, particularly among citrus species.