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Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases
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Vasoocclusion with homozygous hemoglobin-C disease

J A Fort1, J R Graham-Pole, J Chopik

  • 1Division of Pediatric Hematology-Oncology, University of Florida, Gainesville 32611.

The American Journal of Pediatric Hematology/Oncology
|January 1, 1988
PubMed

Hemoglobin-CC is a relatively uncommon hemoglobinopathy, seen primarily in the black population. These patients usually have a mild clinical course, without significant risk of vasoocclusive crises. There are no routine recommendations for preparation prior to surgery. We present a patient who developed a clinical picture suggestive of major vasoocclusion after cardiac by-pass surgery. In retrospect, these signs appear to be the result of hemodynamic instability and cardiogenic shock instead of vasoocclusion.

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