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Updated: Dec 21, 2025

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
Published on: October 14, 2025
Updates in diagnosis and management of inflammatory bowel disease
Kelly Sandberg1, Elizabeth Yarger2, Shehzad Saeed1
1Department of Pediatric Gastroenterology, Dayton Children's Hospital, United States; Boonshoft School of Medicine, Wright State University, Dayton, OH, United States.
Abstract:
Worldwide incidence of inflammatory bowel disease (IBD) is stable in developed countries, but rising in developing countries. Presenting symptoms of IBD can be highly variable. New imaging modalities, a greater armamentarium of therapeutic options, and a greater understanding of complication risks have changed the diagnosis and management of pediatric inflammatory bowel diseases. Effective teamwork among those who care for pediatric patients with IBD minimizes complications and maximizes desired outcomes.
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