Estimation of size-specific dose estimates (SSDE) for paediatric and adults patients based on a single slice
Abdullah Abuhaimed1, Colin J Martin2
1King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia.
Abstract:
Volume averaged CT dose index (CTDIvol) is an important dose index utilized for CT dosimetry. Measurements of CTDIvol are performed in reference cylindrical phantoms of specified diameters. A size-specific dose estimate (SSDE) has been recommended for assessment of doses delivered to individual patients. Evaluation of the SSDE requires the size of the scanned region of the patient to be estimated in terms of water-equivalent diameter (Dw) to allow calculation of a dose value appropriate for the patient. Estimation of Dw, however, may be challenging and time consuming as it requires assessment of Dw for each slice within the scanned region. A study has been carried out to investigate the suitability of using Dw,mid for a single slice at the middle of the scanned region to estimate a value of Dw,mean to apply to all slices. 351 phantoms (158 paediatric and 193 adult) developed from reconstructed CT images of patients were employed. Six scan regions were studied: chest, abdomen, pelvis, chest and abdomen, abdomen and pelvis, and the whole trunk. Results show that the use of Dw,mid can lead to over or underestimation of Dw,mean by up to 13% for paediatric and adult patients. SSDE values based on Dw,mid and Dw,mean were assessed for each phantom, and a linear regression analysis was performed. Use of the analysis could provide a simple and practical approach to assessing SSDE for a given scan based on Dw,mid with the root-mean-square errors estimated to be in the range of 1.2%-4.0% for paediatric and 1.2%-5.9% for adults.
More Related Videos
Related Concept Videos
Drug Dosing: Infants and Children
Dose Size and Dosing Frequency: Determination Methods
Pharmacokinetics in Pediatric Patients: Drug Distribution


