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Adolescent and Parent Perceptions about Participation in Biomedical Sexual Health Trials
Sara E Landers1, Jenny K R Francis2, Marilyn C Morris3
1Research coordinator in the Department of Pediatrics at Vagelos College of Physicians and Surgeons at Columbia University Irving Medical Center.
Ethics & Human Research
|May 19, 2020
Summary
Adolescents need inclusion in sexual health trials for effective interventions. Evidence reviews adolescent and parent willingness, consent, and involvement to improve trial participation.
Area of Science:
- Public Health
- Clinical Trials
- Adolescent Health
Background:
- High burden of HIV and STIs among adolescents necessitates their inclusion in sexual health research.
- Adolescents are often underrepresented in clinical trials, potentially limiting the development of tailored interventions.
Purpose of the Study:
- To review evidence on adolescent and parental willingness to participate in biomedical sexual health trials.
- To examine parental involvement in the consent process and throughout study participation.
- To identify recommendations for improving adolescent representation in clinical trials.
Main Methods:
- Systematic review of existing evidence on adolescent and parental attitudes towards trial participation.
- Analysis of factors influencing willingness, consent, and ongoing involvement.
- Synthesis of recommendations for research practice and future studies.
Main Results:
- Evidence on adolescent and parental willingness for participation in sexual health trials is presented.
- Key considerations for parental consent, managing disagreements, and sustained involvement are discussed.
- Gaps in current practice and research are identified.
Conclusions:
- Ensuring adolescent participation in sexual health trials is crucial for developing safe and effective interventions.
- Addressing parental involvement and consent processes is vital for successful trial recruitment and retention.
- Further research is needed to optimize adolescent engagement in biomedical sexual health research.
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