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Updated: Dec 21, 2025

Author Spotlight: Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
Published on: July 21, 2023
Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles
Yun Luo1, Yu Xiao1, Delphine Onidas1
1Université de Paris, LCBPT, UMR 8601, F-75006 Paris, France. claire.mangeney@parisdescartes.fr yun.sun@parisdescartes.fr.
Abstract:
Surface-enhanced Raman scattering (SERS) tags are usually prepared by immobilizing Raman reporters on plasmonic nanoparticles (NPs) via thiol-based self-assembled monolayers. We describe here the first example of SERS tags obtained by combining gold NPs and aryl diazonium salts. This strategy results in robust Au-C covalent bonds between the Raman reporter and the NPs, thus ensuring a high stability of the nanohybrid interface.
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