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Updated: Dec 20, 2025

Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers
Published on: May 5, 2016
Reconfigurable Integrated Optofluidic Droplet Laser Arrays
Han Zhang1, Prithviraj Palit1, Yonghao Liu1
1Department of Electrical Engineering, University of Texas at Arlington, Arlington, Texas 76019, United States.
Abstract:
Optofluidic lasers are an emerging technology for the development of miniaturized light sources and biological and chemical sensors. However, most optofluidic lasers demonstrated to date are operated at the single optical cavity level, which limits their applications in high-throughput biochemical sensing, high-speed wavelength switching, and on-chip spectroscopic analysis. Here, we demonstrated an optofluidic droplet laser array on a silicon chip with integrated microfluidics, in which four individual droplet optical cavities are generated and controlled by a 2 × 2 nozzle array. Arrays of droplets with a diameter ranging from 115 to 475 μm can be generated, removed, and regenerated on demand. The lasing threshold of the droplet laser array is in the range of 0.63-2.02 μJ/mm2. An image-based lasing threshold analysis method is developed, which enables simultaneous lasing threshold measurement for all laser units within the laser array using a low-cost camera. Compared to the conventional spectrum-based threshold analysis method, the lasing threshold obtained from the image-based method showed consistent results. Our droplet laser array is a promising technology in the development of cost-effective and integrated coherent light source on a chip for point-of-care applications.

