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Updated: Dec 20, 2025

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Gastrointestinal Endoscopy in the Neonate
Ethan A Mezoff1, Kent C Williams2, Steven H Erdman2
1Center for Intestinal Rehabilitation and Nutrition Support, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA; Division of Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA.
Neonatal gastrointestinal endoscopy offers direct visualization and tissue sampling for diagnosis and treatment. Specialized tools enable procedures like feeding tube placement and stenosis dilation in infants, improving care for this vulnerable group.
Area of Science:
- Pediatric Gastroenterology
- Neonatal Medicine
- Medical Technology
Background:
- Gastrointestinal endoscopy allows direct visualization of the alimentary tract.
- Acquisition of mucosal tissue for histopathologic examination is possible.
- Diagnostic and therapeutic maneuvers can be performed.
Purpose of the Study:
- To highlight the expanded capabilities of neonatal gastrointestinal endoscopy.
- To discuss the application of endoscopy in neonates for various conditions.
- To emphasize the importance of careful risk-benefit analysis for patient-specific application.
Main Methods:
- Utilizes endoscopes and compatible tools designed for neonates.
- Describes procedures such as evaluation of gastrointestinal bleeding.
- Includes evaluation and dilation of congenital esophageal stenosis.
- Mentions bedside placement of gastrostomy tubes.
Main Results:
- Endoscopic capabilities have been broadened for neonatal care.
- Specific applications include managing bleeding, esophageal stenosis, and feeding tube placement.
- Limited neonatal-specific data currently exists to guide practice.
Conclusions:
- Neonatal gastrointestinal endoscopy is a valuable tool for diagnosis and therapy.
- Careful consideration of risks, benefits, and interdisciplinary communication is crucial.
- Patient-specific application of these techniques can augment care for vulnerable neonates.
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