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Author Spotlight: Biological Standardization to Ensure Reproducibility and Harmonization in Research
Published on: August 4, 2023
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Addressing selective reporting of experiments through predefined exclusion criteria.
Kleber Neves1, Olavo B Amaral1
1Institute of Medical Biochemistry Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Elife
|May 23, 2020
Summary
Life science researchers often omit failed experiments, causing reporting bias. Predefining exclusion criteria can balance research clarity and thoroughness, improving scientific integrity.
Area of Science:
- Life Sciences
- Scientific Publishing
Background:
- Research articles often prioritize clear narratives, leading to the exclusion of unsuccessful experiments.
- Excluding experiments post-data analysis can introduce reporting bias into scientific literature.
Purpose of the Study:
- To discuss the balance between narrative clarity and comprehensive reporting in life sciences research.
- To propose predefining exclusion criteria as a method to mitigate reporting bias.
Main Methods:
- Discussion of current practices in scientific reporting.
- Analysis of the implications of excluding non-working experiments.
Main Results:
- The practice of excluding 'failed' experiments can lead to significant reporting bias.
- A clear story in research papers may come at the cost of complete data representation.
Conclusions:
- Researchers should consider predefining criteria for experiment exclusion before data collection.
- Adopting predefined exclusion criteria can enhance the thoroughness and reduce bias in research reporting.
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