[Mixed desmoplastic melanoma]
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Updated: Dec 20, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Carina Simionato1, Carla Minaudo1, Tomás Mosquera1
1Servicio Dermatología, Hospital Británico de Buenos Aires, Argentina.
Abstract:
Desmoplastic melanoma is a rare presentation of melanoma with a different clinical behavior compared to other histological variants. Its diagnosis in early stages is a challenge due to its variable clinical presentation, with a predominant dermal component and the frequent absence of pigment. Its histology is divided into pure and mixed type, and this classification has important prognostic implications. The average Breslow thickness at diagnosis is higher than in other melanoma variants. However, the tendency to lymph node metastasis is low.
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