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Updated: Sep 27, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Abstract:
Concepts of nonskeletal forms of fluorosis are set forth in the light of the author's own investigations and reports in the available literature. Descriptions of pathology of the central nervous system, skeletal musculature, stomach, liver, kidney, cardiovascular system, retina, and the skin are presented. The evidences obtained indicate that disturbances in soft tissues in chronic intoxication with fluorine develop early, usually long before the onset of typical changes in teeth and skeletal bones; these changes characterize the preskeletal phase of fluorosis.
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