Related Experiment Video
Updated: Dec 20, 2025

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Published on: January 30, 2020
Survival from Out-of-Hospital Cardiac Arrest - Comparing the Automated LUCAS-2 Device and Manual CPR
Sabina Kupershmidt1, Ramu G Sudhagoni2, Max D Fuller3
1Department of Nursing, University of South Dakota.
Compression-only cardiopulmonary resuscitation (CPR) showed better survival to the emergency department than the automated LUCAS-2 device in a large U.S. study. Enhanced training may improve outcomes with mechanical devices.
Area of Science:
- Emergency Medicine
- Cardiopulmonary Resuscitation
- Medical Devices
Background:
- Cardiopulmonary resuscitation (CPR) competency is crucial in emergency medicine.
- Understanding factors influencing CPR effectiveness is vital for patient outcomes.
- Automated chest compression devices are increasingly used in emergency medical services (EMS).
Purpose of the Study:
- To evaluate the impact of the LUCAS-2 automated device on survival to the emergency department (ED).
- To compare the effectiveness of LUCAS-2 assisted CPR versus manual CPR in a large dataset.
- To analyze CPR outcomes in a predominantly rural U.S. state.
Main Methods:
- Retrospective analysis of electronic Patient Care Reports (ePCR) from South Dakota (2013-2015).
- Primary outcome measure: survival to ED.
- Comparison of survival odds between manual CPR and LUCAS-2 assisted CPR.
Main Results:
- The LUCAS-2 device was used in 15% of 1,781 cases.
- Compression-only CPR demonstrated an odds ratio of 3.94 for survival to ED compared to LUCAS-2.
- These findings remained significant after adjusting for covariates.
Conclusions:
- Compression-only CPR appears more effective than LUCAS-2 assisted CPR for out-of-hospital cardiac arrest (OHCA).
- Despite laboratory benefits, real-world OHCA data suggest manual CPR yields better survival to ED.
- Further research and enhanced provider training are recommended to optimize outcomes with mechanical CPR devices.
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation II: ACLS Airway Management
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

