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Anterior segment optical coherence tomography imaging in peripheral ulcerative keratitis, a corneal structural
Clemence Bonnet1,2, Louis Debillon3, Saba Al-Hashimi4
1Ophthalmology Department, Cochin Hospital, Paris University, Paris, France. clemence.p.bonnet@gmail.com.
BMC Ophthalmology
|May 27, 2020
Summary
Anterior segment optical coherence tomography (AS OCT) reveals distinct corneal changes in peripheral ulcerative keratitis (PUK). These AS OCT findings correlate with disease activity, aiding in diagnosis and monitoring of PUK.
Area of Science:
- Ophthalmology
- Medical Imaging
- Corneal Diseases
Background:
- Anterior segment optical coherence tomography (AS OCT) is valuable for corneal conditions.
- AS OCT has not been previously reported for peripheral ulcerative keratitis (PUK).
Purpose of the Study:
- To describe AS OCT findings in patients with PUK.
- To evaluate the utility of AS OCT in diagnosing and monitoring PUK.
Main Methods:
- Retrospective observational case series of six eyes with PUK and systemic vasculitis.
- AS OCT, clinical course, and slit lamp photography were analyzed.
Main Results:
- AS OCT findings correlated with PUK activity: acute (epithelial absence, stromal changes), reducing activity (irregular epithelium, smoother stroma), and healed stages (epithelial filling, demarcation line).
- Corneal thickness increased significantly from onset to follow-up (408 μm to 509 μm).
Conclusions:
- AS OCT effectively assesses structural changes in PUK.
- AS OCT is a useful tool for the diagnosis and monitoring of peripheral ulcerative keratitis.
