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Related Concept Videos

The Tumor Microenvironment02:17

The Tumor Microenvironment

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

Updated: Dec 20, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
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Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

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[How tumors partner with the brain ?]

Claire Magnon1

  • 1UMR1274 (Équipe cancer et microenvironnement-Inserm-CEA), Institut de radiobiologie cellulaire et moléculaire, Institut de biologie François Jacob, Direction de la recherche fondamentale, 18 route du panorama, 92265 Fontenay-aux-Roses, France.

Medecine Sciences : M/S
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PubMed
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No abstract available in PubMed .

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