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Updated: Jun 11, 2025

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain
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What a wonderful world!

Claire Magnon1

  • 1Laboratory of Cancer and Microenvironment-National Institute of Health and Medical Research (INSERM), Institute of Biology François Jacob-Atomic Energy Commission (CEA), University of Paris Cité, University of Paris-Saclay, Paris 75000, France claire.magnon@inserm.fr.

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Cancer disrupts the body's internal balance by hijacking the brain and its neural networks. This study explores the bidirectional communication between brain and tumors, impacting overall homeostasis.

Keywords:
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Area of Science:

  • Neuroscience and Oncology
  • Brain-Body Communication
  • Cancer Biology

Background:

  • Traditional cancer research focused on genetics and the tumor microenvironment.
  • Emerging evidence indicates tumors can manipulate neural networks.
  • Maintaining whole-body homeostasis relies on intact brain-body circuits.

Purpose of the Study:

  • To explore the paradigm shift connecting cancer science and neuroscience.
  • To investigate how tumors disrupt physiological brain-body communication.
  • To understand the bidirectional nature of brain-tumor interactions.

Main Methods:

  • Review of emerging evidence on neural hijacking by tumors.
  • Analysis of cancer's impact on brain-body circuits.
  • Exploration of interoception, immunoception, and nociception in cancer.

Main Results:

  • Malignant tumors can hijack the brain and peripheral/central neurons.
  • Tumors act as disruptors of bodily homeostasis.
  • Bidirectional brain-tumor connections are implicated in cancer progression.

Conclusions:

  • Cancer significantly disturbs physiological brain-body communication.
  • The brain plays a crucial role in cancer's disruption of homeostasis.
  • Understanding brain-tumor interactions is vital for future cancer research.