Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 20, 2025

Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.9K

Emerging Approaches to Functionalizing Cell Membrane-Coated Nanoparticles.

Xiangzhao Ai1, Shuyan Wang1, Yaou Duan1

  • 1Department of NanoEngineering, Chemical Engineering Program, and Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, United States.

Biochemistry
|May 27, 2020
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multifunctional composite film comprising a citric acid-crosslinked polysaccharide matrix loaded with nutmeg essential oil nanoemulsion: suitable for facilitating active wound healing.

Biomaterials advances·2026
Same author

A Cold- and Salt-Tolerant GH43-1 β-Xylosidase from Cellulomonas bogoriensis 69B4<sup>T</sup>: Biochemical Characterization and Subfamily Functional Diversity.

Applied biochemistry and biotechnology·2026
Same author

From metabolic dysregulation to clinical alert: a novel panel of biomarkers for staging alcohol-associated liver disease.

Journal of translational medicine·2026
Same author

CSF ctDNA Molecular Clearance as a Prognostic Biomarker for Orelabrutinib-Treated Primary Central Nervous System Lymphoma: Insights From Comparison With PET-CT.

American journal of hematology·2026
Same author

Translational bottlenecks for biohybrid microrobots.

Science robotics·2026
Same author

Engineering a GelMA Hydrogel-Based Biomimetic Endometrium-on-a-Chip for Studying Embryo Implantation.

ACS biomaterials science & engineering·2026

Researchers are enhancing cell membrane-coated nanoparticles by adding new functions. Emerging methods like lipid insertion and genetic modification improve their adaptability for complex biological systems.

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Cell Biology

Background:

  • Cell membrane-coated nanoparticles (CMCNPs) offer biomimicry and biointerfacing advantages.
  • Expanding CMCNPs' utility requires integrating functions beyond natural cell membranes.

Purpose of the Study:

  • To review recent advancements in functionalizing CMCNPs.
  • To highlight novel methods for enhancing CMCNP capabilities.

Main Methods:

  • Lipid insertion into cell membranes.
  • Membrane hybridization techniques.
  • Metabolic engineering of cell membranes.
  • Genetic modification for functionalization.

Main Results:

  • These methods introduce diverse functionalities without disrupting natural membrane properties.

More Related Videos

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
10:16

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier

Published on: February 8, 2017

7.9K
Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
07:31

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

6.4K

Related Experiment Videos

Last Updated: Dec 20, 2025

Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.9K
Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
10:16

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier

Published on: February 8, 2017

7.9K
Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
07:31

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis

Published on: July 16, 2020

6.4K
  • Functionalization enhances the multifunctional and multitasking abilities of CMCNPs.
  • Improved adaptability of CMCNPs for complex biological environments.

    • Conclusions:

    • Emerging functionalization strategies significantly advance CMCNP technology.
    • These approaches enable CMCNPs to better interact with complex biological systems.
    • Further innovation in functionalization will broaden CMCNP applications.