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Development and Performance of Bioactive Compounds-Loaded Cellulose/Collagen/Polyurethane Materials.
Iuliana Spiridon1, Narcis Anghel1, Maria Valentina Dinu1
1"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Polymers
|May 28, 2020
Summary
Researchers developed a new cellulose, collagen, and polyurethane biomaterial. Incorporating tannin and lipoic acid enhanced its antioxidant capacity and mechanical properties for cosmetic applications.
Area of Science:
- Materials Science
- Biomaterials Engineering
- Cosmetic Science
Background:
- Development of advanced biomaterials is crucial for enhanced product performance.
- Antioxidant properties and mechanical strength are key parameters for cosmetic formulations.
Purpose of the Study:
- To create a novel biomaterial matrix using cellulose, collagen, and polyurethane.
- To incorporate bioactive compounds like tannin and lipoic acid for enhanced functionality.
- To evaluate the mechanical, mucoadhesive, and antioxidant properties of the developed biomaterial.
Main Methods:
- Dissolution of cellulose, collagen, and polyurethane in butyl imidazole chloride.
- Incorporation of tannin and lipoic acid into the biomaterial matrix.
- Assessment of compressive strength, mucoadhesiveness, controlled release, and antioxidant capacity.
Main Results:
- The biomaterial exhibited increased compressive strength (105-139 kPa) after bioactive incorporation.
- Mucoadhesiveness increased by 29.85% with tannin, indicating prolonged bioavailability.
- Antioxidant capacity was enhanced by 40%-50% compared to the base matrix.
Conclusions:
- The developed biomaterial demonstrates superior mechanical and antioxidant properties.
- Enhanced mucoadhesiveness and controlled release characteristics are beneficial for active substance delivery.
- These findings support the use of these biomaterials in cosmetic masks and patches.
