Role of Ultra-widefield Imaging in Eales' Disease: A Case Series

Purpose: To describe and quantify the benefit of ultra-widefield imaging in cases of Eales' disease during primary and follow-up visits. Methods: This was a retrospective cross-sectional observational study screening case records of Eales' disease patients. Disease activity of each patient visit was assessed on clinical examination with indirect-ophthalmoscopy, ultra-widefield images (Optos) and widefield fluorescein angiography (FA) images. Clinical examination and Optos findings were compared with FA.The outcome measure was whether Optos and FA imaging helped in detecting disease activity better than clinical examination. Results: In total, 57 visits of 32 Eales'disease patients were analyzed. Disease activity was detected in 10/57 (17.5%) patient visits on clinical examination and in 20/57 (35%) patient visits on Optos. FA detected 29/57 (50.9%) patient visits as active vasculitis. Patient visits detected to have active vasculitis were significantly more with Optos and FA as compared to clinical examination (p = .017&0.0001, respectively). Widefield FA detected significantly more number of active vasculitis as compared to Optos (p = .043). Conclusion: Ultra-widefield imaging is a very helpful tool in the management of a patient with Eales'disease.