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Preworkout Supplement Induced Hemorrhagic Stroke: A Case Report
Alycia N Amatto1, Michael D Amatto2, Jaime C Yu2
1Faculty of Medicine & Dentistry, MD Program, University of Alberta, Edmonton, AB, Canada; and.
Summary
Preworkout supplements may increase the risk of hemorrhagic stroke, even in young, healthy individuals. One case involved a 24-year-old man whose supplement contained Dendrobium extract, a precursor to amphetamine.
Area of Science:
- Neurology
- Toxicology
- Cardiovascular Medicine
Background:
- Hemorrhagic stroke is a significant cause of death and disability.
- Many risk factors for stroke are modifiable.
- Preworkout supplements are widely used, particularly by young adults.
Observation:
- A previously healthy 24-year-old male presented with a spontaneous hemorrhagic stroke.
- The patient reported regular consumption of preworkout supplements.
- No other significant risk factors for stroke were identified.
Findings:
- The preworkout supplement contained Dendrobium extract.
- Dendrobium extract contains B-phenylethylamine, an amphetamine precursor.
- This suggests a potential link between supplement ingredients and stroke occurrence.
Implications:
- Highlights the potential for commercially available supplements to harbor dangerous, unlisted ingredients.
- Underscores the need for further research into the cardiovascular risks associated with preworkout supplements.
- Emphasizes the importance of thorough patient history, including supplement use, in cases of unexplained stroke.
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