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Updated: Dec 20, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
[Opioids in palliative care]
Selina Späni1, Christine Zobrist1
1Medizinische Universitätsklinik, Kantonsspital Baselland (KSBL), Liestal.
Opioids are crucial for managing symptoms like pain and shortness of breath in palliative care. Individualized treatment plans are essential to maximize benefits and minimize adverse drug reactions for patients with incurable illnesses.
Area of Science:
- Palliative Care Medicine
- Pain Management
- Pharmacology
Background:
- Palliative care addresses complex needs of patients with incurable illnesses.
- Symptom burden, including pain and dyspnea, is common.
- Optimizing quality of life is a primary goal.
Purpose of the Study:
- To highlight the role of opioids in palliative care.
- To emphasize individualized opioid selection, dosing, and administration.
- To underscore the importance of holistic patient management.
Main Methods:
- Review of current practices in palliative care opioid management.
- Emphasis on personalized patient assessment.
- Integration of physical, psychological, social, and spiritual care.
Main Results:
- Opioids are vital for symptom control in palliative care.
- Individualized approaches are necessary to balance efficacy and adverse effects.
- Addressing non-physical needs is integral to comprehensive care.
Conclusions:
- Opioid therapy requires careful, patient-specific consideration in palliative settings.
- An interprofessional approach is essential for holistic patient management.
- Maximizing quality of life involves managing both physical and non-physical symptoms.
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