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Updated: Dec 19, 2025

Divergence of Root Microbiota in Different Habitats based on Weighted Correlation Networks
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Earth microbial co-occurrence network reveals interconnection pattern across microbiomes.

Bin Ma1,2, Yiling Wang1, Shudi Ye1

  • 1College of Environmental and Resource Sciences, Zhejiang University, Institute of Soil and Water Resources and Environmental Science, Hangzhou, 310058, China.

Microbiome
|June 6, 2020
PubMed
Summary
This summary is machine-generated.

This study reveals global microbial co-occurrence patterns across diverse environments. It highlights environment-specific microbial relationships and identifies key microbial hubs, offering a network perspective on microbiome structure.

Keywords:
Co-occurrence patternsEarth microbiomesGenelist edgesMicrobial network topologyNegative co-occurrenceNetwork hubsSpecialist edges

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Area of Science:

  • Microbial ecology
  • Network analysis
  • Bioinformatics

Background:

  • Microbial interactions are crucial for community structure and function.
  • Microbial co-occurrence networks explore complex systems.
  • Global interconnection patterns across diverse microbiomes remain unexplored.

Purpose of the Study:

  • To infer an Earth microbial co-occurrence network.
  • To explore interconnection patterns across diverse environments globally.
  • To understand environment-specific microbial co-occurrence relationships.

Main Methods:

  • Inferred an Earth microbial co-occurrence network.
  • Utilized a communal catalog of 23,595 samples and 12,646 exact sequence variants.
  • Analyzed data from 14 environments in the Earth Microbiome Project dataset.

Main Results:

  • An Earth microbial co-occurrence network with 8 distinct modules linked to environments was constructed.
  • Environment-specific co-occurrence patterns and specialist edges were identified.
  • Microbiomes clustered into two groups, bridged by plant and animal surface microbiomes; Acidobacteria Gp2 and Nisaea were identified as hubs.

Conclusions:

  • Microbial co-occurrence features are essential across microbiomes.
  • Environmental specificity shapes microbial relationships.
  • A network perspective is crucial for understanding microbiome interconnection patterns.