Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...

Biological Methods for Microbial Control

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Territorial Ecological Restoration Zoning and Diagnosis of the Upper Reaches of the Yangtze River Shoreline in the Chongqing Section].

Huan jing ke xue= Huanjing kexue·2026

Same author

[Effects of drought stress on phenotypic traits and physiological characteristics of three <i>Poa</i> forage species].

Ying yong sheng tai xue bao = The journal of applied ecology·2026

Same author

Expression of concern: Bacterial self-defense antibiotics release from organic-inorganic hybrid multilayer films for long-term anti-adhesion and biofilm inhibition properties.

Nanoscale·2023

Same author

Supramolecular Nano-Assembly of Caffeate-Strengthened Phenylboronic Ester with Multistep ROS Scavenging Ability for Targeted Therapy of Acute Kidney Injury.

Advanced healthcare materials·2023

Same author

Metabolic reprogramming of the glutathione biosynthesis modulates the resistance of <i>Salmonella</i> Derby to ceftriaxone.

iScience·2023

Same author

Enhanced Transcutaneous Chemodynamic Therapy for Melanoma Treatment through Cascaded Fenton-like Reactions and Nitric Oxide Delivery.

ACS nano·2023

Same journal

Fiber and continuum scale contributions to the intrinsic and apparent fracture of soft collagenous tissue <i>via</i> cutting.

Biomaterials science·2026

Same journal

Surface morphology-regulated tissue adhesion in solid and mesoporous silica-reinforced gelatin nanocomposite hydrogels.

Biomaterials science·2026

Same journal

Nanostructured hyaluronic acid-chia mucilage film as bioactive wound dressings for accelerated skin regeneration.

Biomaterials science·2026

Same journal

Tunable bio-inspired hybrid hydrogels reprogram stem cell-derived extracellular vesicles for superior wound regeneration.

Biomaterials science·2026

Same journal

Bioorthogonally reinforced injectable granular hydrogels synergizing ECM mimicry with microporosity for skin tissue engineering.

Biomaterials science·2026

Same journal

Modeling a hypoxia-integrated glioblastoma microenvironment to mimic tumor heterogeneity and chemoresistance.

Biomaterials science·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 19, 2025

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

Functionalized biomaterials to combat biofilms.

Dan-Ni Huang¹, Jing Wang, Ke-Feng Ren

¹MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China. renkf@zju.edu.cn jijian@zju.edu.cn.

Biomaterials Science

|June 6, 2020

Summary

This summary is machine-generated.

This review explores strategies for combating established pathogenic microbial biofilms on medical devices and tissues. It highlights functionalized biomaterials and current methods for eradicating these persistent infections, offering a blueprint for the postantibiotic era.

More Related Videos

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

Related Experiment Videos

Last Updated: Dec 19, 2025

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

Area of Science:

Biomaterials Science
Microbiology
Infectious Diseases

Background:

Pathogenic microbial biofilms pose a significant threat to healthcare, particularly on implantable medical devices and human tissues.
The challenge of tackling established biofilms, rather than just preventing them, remains a critical unmet need.

Purpose of the Study:

To review functionalized biomaterials designed to combat microbial biofilms.
To highlight current approaches for the eradication of pre-existing biofilms.
To propose a blueprint for fighting biofilm-associated infections in the postantibiotic era.

Main Methods:

Literature review of functionalized biomaterials.
Analysis of current biofilm eradication strategies.
Synthesis of findings to propose future directions.

Main Results:

Summary of various functionalized biomaterials with anti-biofilm properties.
Overview of emerging and established methods for eradicating established biofilms.
Identification of potential synergistic or combinatorial therapeutic approaches.

Conclusions:

Functionalized biomaterials and novel eradication strategies offer promising avenues to combat established biofilms.
A combination of approaches may be necessary for effective treatment of biofilm-associated infections.
These strategies are crucial for managing infections in the postantibiotic era.